Aiming at the problems of environmental disturbance, hidden structural response, and difficult collaborative fusion of multi source monitoring information in the long-term preservation process of mobile cultural relics, this paper proposes a digital twin construction and real time status monitoring method for the Changxin Palace Lantern based on multi-mode perception data fusion. This paper constructs a multi-source sensing system integrating 3D structured light, spectral imaging, FBG strain sensing and MEMS vibration monitoring, and realizes the unified representation of geometric state, material characteristics and dynamic response of cultural relics through asynchronous spatio temporal registration and a physical constraint driven spatio temporal fusion network (ATS FusionNet). On this basis, the residual driven state deviation index (RSDI) is established to realize the location of abnormal areas and the identification of degradation risks. The experiment is carried out based on the joint verification platform of Changxin Palace Lantern. The results show that the mean absolute errors of temperature prediction, strain prediction, and vibration amplitude prediction in the multi-mode state field reconstruction is 0.31 ℃, 2.7με and 0.012g, respectively. The end-to-end response delay of the system is 43.6ms on average, meeting the requirements of real-time monitoring. The research shows that the proposed method can effectively break through the limitations of insufficient single-mode perception and lack of physical correlation in the traditional cultural relic monitoring and provide a high-precision and real-time digital twin technology path for the intelligent protection and preventive maintenance of complex mobile cultural relics.